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学位论文
- 作者：
孟永梅 （ 内蒙古医学院 ） - 学位名称： 硕士
- 出处： 内蒙古医学院 2004
- 关键词： 蒙成药 苦参七味胶囊 制备工艺
- 摘要： 目的:传统苦参七味汤味苦难咽,煎煮麻烦、质量难以控制、难以达到国家标准等不足之处加以弥补,在蒙药方剂理论指导下制成苦参七味胶囊的新剂型.方法:首先按组方药苦参、土木香、诃子、川楝子、栀子、胡黄连、肋柱花的主要有效成分及理化性质制定出三种工艺路线,即工艺一、工艺二、工艺三;其次利用简单药效学实验,筛选
期刊
- 作者：
Ang Ge-Li-ma ，Bao Su-ri-gao ，Meng Yong-mei （ 1Inner Mongolia Med Univ, Mongolian Med Basic Expt Ctr, Mongolian Med Sch, Hohhot 010110, Peoples R China ） - 出处： Chinese Pharmacological Bulletin 2022 Vol.38 No.7 P1099-1106
- 摘要： Aim To study the protective effect of Mongolian medicine rhubarb-3 decoction on renal function of CRF model rats and explore its mechanism. Methods SD
- 作者：
Zhaomeng Cui ，Yang Liu ，Wei Wan ，Yuyan Xu ，Yehui Hu ，Meng Ding ，Xin Dou ，Ruina Wang ，Hailing Li ，Yongmei Meng ，Wei Li ，Wei Jiang ，Zengxia Li ，Yiming Li ，Minjia Tan ，Dengke K. Ma ，Yu Ding ，Jun O. Liu ，Cheng Luo ，Biao Yu ，Qiqun Tang ，Yongjun Dang （ Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China. Institute of Stem Cell Research and Regenerative Medicine, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200030, China. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, 200438, China. Henan Sesame Research Center, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China. College of Traditional Mongolian Medicine, Inner Mongolia Medical University, Mongolia, 010110, China. State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, 200040, China. Department of Physiology, Cardiovascular Research Institute, University of California San Francisco, San Francisco, USA. Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. cluo@simm.ac.cn. State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. byu@sioc.ac.cn. Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China. qqtang@shmu.edu.cn. Institute of Stem Cell Research and Regenerative Medicine, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200030, China. qqtang@shmu.edu.cn. Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China. yongjundang@fudan.edu.cn. ） - 出处： Protein & Cell 2021 Vol.12 No.6 P493-501
- 作者：
Zhaomeng,Cui ，Yang,Liu ，Wei,Wan ，Yuyan,Xu ，Yehui,Hu ，Meng,Ding ，Xin,Dou ，Ruina,Wang ，Hailing,Li ，Yongmei,Meng ，Wei,Li ，Wei,Jiang ，Zengxia,Li ，Yiming,Li ，Minjia,Tan ，Dengke K,Ma ，Yu,Ding ，Jun O,Liu ，Cheng,Luo ，Biao,Yu ，Qiqun,Tang ，Yongjun,Dang （ Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China. '(1)' ; Institute of Stem Cell Research and Regenerative Medicine, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200030, China. [2] ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. [3] ; Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, 200438, China. [4] ; Henan Sesame Research Center, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China. [5] ; College of Traditional Mongolian Medicine, Inner Mongolia Medical University, Mongolia, 010110, China. [6] ; State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. [7] ; Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, 200040, China. [8] ; Department of Physiology, Cardiovascular Research Institute, University of California San Francisco, San Francisco, USA. [9] ; Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. [10] ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. cluo@simm.ac.cn. [11] ; State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. byu@sioc.ac.cn. [12] ; Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China. qqtang@shmu.edu.cn. [13] ; Institute of Stem Cell Research and Regenerative Medicine, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200030, China. qqtang@shmu.edu.cn. [14] ; Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China. yongjundang@fudan.edu.cn. [15] ） - 出处： Protein & cell
- 作者：
孟永梅 ，王伟 （ 内蒙古医科大学；北京中医药大学 ） - 出处： 世界中医药 2018 13卷 第9期 P2111-2116
- 关键词： 慢性心力衰竭 中医证候 iTRAQ技术 蛋白质组学
- 摘要： 目的:寻找慢性心力衰竭(CHF)(Chronic Heart Failure,CHF)气虚血瘀证及气阴两虚证的相关蛋白质组学特征,探讨证候发生发展机制的可能生物学通路。方法:研究设计分为CHF气虚血瘀证、气阴两虚证、健康对照组,利用i TRAQ标记定量结合串联质谱技术分析CHF气虚血瘀证及气阴两虚证
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被引量：4
- 作者：
Zhaomeng Cui ，Yang Liu ，Wei Wan ，Yuyan Xu ，Yehui Hu ，Meng Ding ，Xin Dou ，Ruina Wang ，Hailing Li ，Yongmei Meng ，Wei Li ，Wei Jiang ，Zengxia Li ，Yiming Li ，Minjia Tan ，Dengke K.Ma ，Yu Ding ，Jun O.Liu ，Cheng Luo ，Biao Yu ，Qiqun Tang ，Yongjun Dang （ Key Laboratory of Metabolism and Molecular Medicine，The Ministry of Education，Department of Biochemistry and Molecular Biology，Shanghai Medical College，Fudan University，Shanghai 200030，China；Key Laboratory of Metabolism and Molecular Medicine，The Ministry of Education，Department of Biochemistry and Molecular Biology，Shanghai Medical College，Fudan University，Shanghai 200030，China；Institute of Stem Cell Research and Regenerative Medicine，Institutes of Biomedical Sciences，Fudan University，Shanghai 200030，China；State Key Laboratory of Drug Research，Shanghai Institute of Materia Medica，Chinese Academy of Sciences，Shanghai 201203，China；Department of Physiology and Biophysics，School of Life Sciences，Fudan University，Shanghai 200438，China；Henan Sesame Research Center，Henan Academy of Agricultural Sciences，Zhengzhou 450002，China；College of Traditional Mongolian Medicine，Inner Mongolia Medical University，Mongolia 010110，China；State Key Laboratory of Bio-organic and Natural Products Chem-istry，Shanghai Institute of Organic Chemistry，Chinese Academy of Sciences，Shanghai 200032，China；Department of Endocrinology and Metabolism，Huashan Hospital，Fudan University，Shanghai 200040，China；Department of Physiology，Cardiovascular Research Institute，University of Califomia San Francisco，San Francisco，USA；Department of Pharmacology and Molecular Sciences，The Johns Hopkins University School of Medicine，Baltimore，MD，USA ） - 出处： 蛋白质与细胞 2021 第12卷 第6期 P493-501
- 摘要： Dear Editor,Obesity is caused by an imbalance between energy intake and expenditure,and has become a global epidemic with over 650 million adults affe
- 作者：
孟永梅 ，韩额尔德木图 ，王呼萍 （ 内蒙古医学院 ） - 出处： 云南中医中药杂志 2010 第11期 P59-60,0
- 关键词： 胡萝卜 正交试验 超临界二氧化碳萃取
- 摘要： 目的:用正交试验优化超临界二氧化碳萃取胡萝卜的工艺条件。方法:以萃取压力、萃取温度和萃取时间为考察因素,用萃取物总量为衡量指标综合考察胡萝卜的萃取工艺。结果:优选出较佳工艺条件为:萃取压力30MPa,萃取温度50℃,萃取时间180 min。结论:本萃取工艺方法简便,操作可行。
- 作者：
韩额尔德木图 ，马月宏 ，王海燕 ，孟永梅 （ 内蒙古医科大学附属医院；内蒙古医科大学 ） - 出处： 中西医结合心脑血管病杂志 2016 第14卷 第12期 P1349-1352
- 关键词： 心衰 病理生理 发病机制
- 摘要： 心力衰竭(心衰),是各种心脏结构或功能性疾病导致心室充盈及(或)射血能力受损而引起的一组综合征。心衰是各种心脏病的严重阶段,其发病率高,正成为21世纪最为重要的心血管病症。针对上述问题,本研究就心衰的病理生理及发病机制的研究进展综述如下。
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被引量：18
- 作者：
韩额尔德木图 ，孟永梅 （ 内蒙古医科大学附属医院；北京中医药大学；内蒙古医科大学 ） - 出处： 中医药学报 2016 第44卷 第3期 P54-60
- 关键词： 慢性心衰 证型 证候要素 理化指标
- 摘要： 目的:研究慢性心衰(CHF)患者中医证候要素与理化指标之间的关系。方法:采用临床流行病学的调查方法,收集慢性心衰患者临床资料,分析统计CHF各证候要素与理化指标相互关系。结果:(1)有统计学差异的阳性理化指标:CHF组有WBC、LYM#、MONO#、NEUT#、RBC、HGB、MCH、MCHC、MP
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被引量：4
- 作者：
孟永梅 ，陈婵 ，王伟 （ 内蒙古医科大学；杭州市萧山区中医院；北京中医药大学 ） - 出处： 天津中医药 2017 第34卷 第7期 P446-450
- 关键词： 慢性心力衰竭 证候 证候要素 心功能
- 摘要： [目的]研究内蒙古自治区呼和浩特市及周边慢性心力衰竭(CHF)患者中医证候规律,探索证候要素分布特点,为中医临床辨证论治提供可鉴思路。[方法]课题组收集入组148例CHF患者临床资料,按照中医诊断标准,统计分析并探讨其分布规律。[结果]CHF病例男女比例0.83∶1,平均年龄(64.6±11.2)岁
- 孟永梅，副教授，博士，硕士研究生导师。目前担任蒙医基础实验中心主任。在科研方面，先后参与过自治区蒙药现代化科技专项4项，教育部国际科技合作项目1项，国家科技重大专项项目1项，国家中医药管理局项目1项，院级项目2项，主要做了基础文献调研及实验室检验工作。在研项目2项，分别是国家自然基金项目“利用 miRNA 芯片技术寻找慢性心衰血瘀证素相关的血清标志物研究；博士启动基金项目“三味大黄汤对肥胖小鼠的药理实验研究”。发表论文15余篇。